Manchester United welcome West Ham to Old Trafford today and the Reds will be aiming to leapfrog Manchester City and Leicester City in the Premier League table if they slip up.
However, they will have to do so with a host of injury problems. Captain Wayne Rooney will be missing after picking up an ankle injury last weekend against the Foxes, while Marcos Rojo dislocated his shoulder in training and he could be out for a month.
They join Ander Herrera, Phil Jones, Luke Shaw and Antonio Valencia on the sidelines and Louis van Gaal will have a headache selecting his side for the 3 pm kick-off.
With a crucial Champions League tie against Wolfsburg on the horizon, who makes our predicted XI?
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