Manchester United travel to the London Stadium knowing that a point will guarantee them a second place finish above Liverpool and Tottenham.
Jose Mourinho’s men will also be looking for a first away win in May since 2016, a 1-0 win against Norwich.
There could be another former player that comes back to haunt the Red Devils in East London, as Javier Hernandez could line-up for the Hammers.
David Moyes’ side are in search of their first back to back Premier League victories since January of last year.
With Premier League survival now secured, there is little pressure on the former Red Devils boss, however, he will want to finish the season strongly with his contract up at the end of the season.
Romelu Lukaku remains injured and will miss this game but Alexis Sanchez and Phil Jones are both back available for selection.
Here’s how we think Man United will line-up for their final away game…
Goalkeeper: David De Gea
PFA team of the year goalkeeper.
Right Back: Antonio Valencia
Has become a top quality full-back under Mourinho.
Centre Back: Eric Bailly
Solid and strong defender.
Centre Back: Phil Jones
Back from injury and back into the 11.
Left Back: Ashley Young
Similar to Valencia, has made the transition into a full-back with ease.
Centre Midfield: Scott McTominay
Young star with a big future.
Centre Midfield: Nemanja Matic
Quality holding midfielder, one of the best around.
Attacking Midfield: Paul Pogba
Pogba comes under criticism but his talent cannot be questioned.
Right Midfield: Jesse Lingard
Enjoying his best season in a red shirt and will be hoping to add to his goal tally.
Left Midfield: Alexis Sanchez
Not had the impact expected when he joined from Arsenal in January bt is a match winner on his day.
Striker: Marcus Rashford
Will need to step up to the plate in the absence of Lukaku.